Here are some of the most frequently asked
questions about BCM (CURCUGREEN®)
Turmeric 95% extract is standardized to 95% curcuminoids consisting of curcumin, demethoxycurcumin and bis-demethoxycurcumin.
BCM-95® (CURCUGREEN®) is standardized to 95% curcuminoid complex containing curcuminoids and turmeric essential oil enriched to 45% ar-turmerone which is a natural active component of the turmeric rhizome that has known health benefits. This also means that BCM-95® (CURCUGREEN®) is 100% Turmeric
BCM-95® (CURCUGREEN®) and has been proven over 300 formulations in over 60 countries over 18 years.
BCM-95®, Curcugreen ® and Biocurcumin® refer to the same product. The product is based on the patent by Arjuna Natural Pvt Limited who is also the manufacturer. BCM-95® (CURCUGREEN®) and Biocurcumin® are trademarks exclusively licensed to Arjuna Natural Pvt Ltd. Curcugreen® is a registered trademark of Arjuna Natural Pvt. Ltd.
BCM-95® (CURCUGREEN®) is manufactured in Arjuna Natural Pvt Limited’s own factories located in India. Arjuna Natural Pvt Ltd is both the patent holder and the manufacturer. What is more, we care of the product even before it reaches our factory, forging relationships with farmers, farming communities and agricultural research organizations to ensure that there is end-to-end quality control.
It is common to combine the action of many ingredients for maximum benefit. BCM-95® (CURCUGREEN®) has been used in over 300 formulations, many of which are combinations and for over 18 years has been highly effective and sought after. This is because, unlike other products which are not 100%turmeric and feature other bio availability enhancers which may affect the impact of co-ingredients or even other drugs, BCM-95® (CURCUGREEN®) is 100% turmeric and the bio enhancer is a 45% concentrated Turmeric Essential oil which is known to act on only curcumin making it safe for using in combination.
The proportion of a drug reaching the systemic circulation upon extravascular administration as compared to that of a standard dose of the drug administered via the same route.
Relative bioavailability implies drug availability obtained without data from intravenous administration. For example, availability comparisons of a drug between two different oral formulations without intravenous data can be thought of as the relative bioavailability of the two different formulations.
For measuring bio availability, the quantity of free curcumin available in the blood plasma after oral ingestion of BCM-95® (CURCUGREEN®) is compared to the similar value obtained when regular Curcumin 95% is ingested. It is the free curcumin in the blood plasma that gives the health benefits of Turmeric
Free Curcumin is freely available in the blood plasma after ingestion of curcumin. Curcumin metabolites, as the name implies are products of metabolism of curcumin in the body. They do not have known health benefits and are inactive for health purposes.
BCM-95® (CURCUGREEN®)is safer than other alternative bioavailable branded curcumins in the market due to many reasons some of which are listed below
- Utilized bio enhancers are specially concentrated essential oils of turmeric have no other side effects unlike other branded curcumins which have non-turmeric bio enhancers which may have drug interactions
- GRAS (Generally Recognized As Safe) Affirmed
- Uses safe extraction means and is checked in the most sensitive instruments for any contaminants
- Lead and other heavy metal safe
- Safe for over 18 years of standing in over 300 formulations in over 60 countries
- The only curcumin for which a detailed toxicity study is published.( Systematic and comprehensive investigation of the toxicity of curcuminoid-essential oil complex: A bioavailable turmeric formulation, MOLECULAR MEDICINE REPORTS 13: 592-604, 2016)
Bio availability of curcumin is increased in BCM-95®(CURCUGREEN®) by a patented proprietary process by which high purity curcumin is synergistically blended with turmeric essential oil which is specifically concentrated to 45% ar-turmerone, an active ingredient of natural turmeric . This produces a 100% turmeric product which is both highly bio active and also safe as it contains no non-turmeric constituent. The ar-turmerone which has synergistic action with curcumin is known to increase the bio availability of only curcumin and not of any other compound minimizing risk of un-intended interactions.
Since the method of bio availability increase in BCM-95® (CURCUGREEN®) is acting only on curcumin and is 100% natural, there are no other known risks or interactions. The other popular methods of aiding bioavailability rely on non-turmeric additives like those used in drug delivery. Unlike the safe method in BCM-95® (CURCUGREEN®), this can pose long term health risks or risks of interference in drug delivery by increasing or decreasing delivered drug quantity. BCM-95® (CURCUGREEN®) has been extensively studied scientifically to be safe and the results published.
A comprehensive study was undertaken (Systematic and comprehensive investigation of the toxicity of curcuminoid-essential oil complex: A bioavailable turmeric formulation, MOLECULAR MEDICINE REPORTS 13: 592-604, 2016) to evaluate the safety of BCM-95® (CURCUGREEN®) and the results published. The detailed toxicity and safety of BCM-95® (CURCUGREEN®) was done using in vivo and in vitro models as per OECD guidelines. Acute toxicity study was performed in rats as well as mice. In this study, no toxic signs and symptoms/mortality was observed in any of the animals at the maximum recommended dose level of 5000 mg/kg b.wt. The repeated administration of BCM-95® (CURCUGREEN®) for 90 days in wistar rats at the dose level of 1000 mg/kg body weight did not induce any observable toxic effects, when compared to its corresponding control animals. Mutagenicity (nontoxicity) studies were also performed by Ames test (Bacterial Reverse Mutation Assay), Mammalian Bone Marrow Chromosome Aberration Test and Mammalian Erythrocyte Micronucleus Test in mice. BCM-95® (CURCUGREEN®) was found to be non-mutagenic in all the three mutagenicity studies. The present study clearly indicates that BCM-95® (CURCUGREEN®) does not have any toxic effects in animals as well as in vitro. Based upon these observations, it is concluded that the BCM-95® (CURCUGREEN®) is non-toxic and safe as evidenced by acute toxicity studies, repeated dose toxicity study and mutagenicity studies.
The definition of bio-availability is well known. The objective of understanding bio-availability is to understand what the real world benefit to the consumer of each quantity ingested is.
Curcuminoids undergo complex transformations in the body once ingested. . The positive health benefits is limited to free cucumin available in the blood plasma ONLY. However, this forms only a part of the total curcuminoids. . Most part of the curcuminoids convert themselves into curcumin metabolites which undergo further changes in the body and are eliminated. This does not provide any health benefit.
However, working back with an objective to hit a higher 'numerical value’, it has been a practice to measure total curcuminoids by measuring the inactive curcumin metabolites as well. This serves two purposes, both of which are not favorable to the consumer.
- It indicates a higher bio activity and the consumer wrongly infers a higher benefit, when this is clearly not the case.
- The effective dosage is reduced, decreasing any benefit further, while the consumer pays more per effective curcumin.
Needless to say, this is very deceptive.
In contrast BCM-95® (CURCUGREEN®) only measures the true free curcumin and ONLY in the extracted blood plasma which gives a very reliable measure of benefit
The bioavailability mechanism of BCM-95® (CURCUGREEN®) has been researched and well understood. The results obtained are in line with scientific theories regarding the same.
On oral intake of curcumin, the P glycoprotein in intestinal cells pushes out curcumin back into the gut lumen which is a major rate limiting step in the absorption of curcumin. BCM-95® (CURCUGREEN®) is a synergistic blend of curcumin and essential oil of turmeric enriched with turmerones. Turmerones in BCM-95® (CURCUGREEN®) inhibit P glycoprotein thereby increases absorption and bioavailability of curcumin in the body. Moreover this mechanism causes repeated absorption cycles which is also evidenced by the presence of free curcumin in the blood plasma even after 8 – 9 hours of ingestion.
The constitution of BCM-95® (CURCUGREEN®) with turmerones is protected by 53 international patents and is unique to BCM-95® (CURCUGREEN®). Hence the effect and efficacy of this process is also unique to BCM-95® (CURCUGREEN®).
A bio available curcumin has two parts: the curcumin (turmeric extract) and the bio-enhancer. An older approach was to provide a simplistic bio enhancer along with a branded regular curcumin -95%. This approach has many drawbacks. It is left to the final producer to blend the two before making supplements. Also the correct ratio cannot always be guaranteed in each dose.
BCM-95® (CURCUGREEN®) was the first to bring a pre formulated product to the market. By synergistically combining curcumin-95% and 45% ar-turmerone enriched turmeric essential oil in a controlled professional environment, BCM-95® (CURCUGREEN®) delivers a consistent product ; consistent in both quality and ratios each time and every time. This translates into predictable and assured benefits as well as less efforts on the part of the supplement manufacturer.
Every batch of BCM-95® (CURCUGREEN®) produced is tested at our in-house lab for heavy metals including lead, arsenic, cadmium and mercury. We use the latest and most accurate lab equipment called “ICP-MS” which can detect even minute quantities of substances instead of less accurate conventional Atomic Absorption.
Every batch of BCM-95® is produced with a lead limit of not more than 0.5 ppm. Most of the available turmeric extracts have a lead limit of 2 ppm or greater.
Yes, BCM-95® (CURCUGREEN®) is non-GMO.
Yes, BCM-95® (CURCUGREEN®) is allergen free
BCM-95® (CURCUGREEN®) is the most researched Bio-available curcumin in the world with more than 64 studies conducted worldwide (geographically diverse) and published in reputed journals. Please see the website a full list published studies. There are also many studies more in various stages of progress or publication.
BCM-95® (CURCUGREEN®) is the world's most researched bio available curcumin. There are 64 published papers as on February 2020 of independent research papers in high impact publications across product categories and combinations and across countries. BCM-95® (CURCUGREEN®) has been very versatile and is also the world's first formulated bio available curcumin . This brings in a high degree of uniformity in product and its action making it a natural choice of research. It is true that there have been claims of higher numbers from other quarters , but this is by counting studies where bio enhancers where not a part and therefore these would really be only studies of a branded curcumin 95% and Not a bioavailable curcumin.
WHY SHOULD YOU CHOOSE
BCM-95® (CURCUGREEN®) ?
- Most researched bio available curcumin in the world
- Highest potency bioavailable turmeric extract
- Over 18 years of market leadership
- Safest bio available curcumin – 100% turmeric & 100% Natural
- Over 53 international patents
- Green Clean and traceable
- Available in over 60 countries in over 300 formulations
- Widest Range of Product variants
- Proven and studied mechanism of action